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Article

Environmental-mediated drug resistance: a target for multiple myeloma therapy

25 Nov 2009

Abstract excerpt

Multiple myeloma is an incurable malignancy of mature clonal B cells. The refractory nature of this disease has long been attributed to the acquisition of drug resistance. Traditionally, mechanisms of drug resistance have been defined by genetic, acquired changes in the expression or function of specific genes products. However, over the past 10 years a large body of evidence has emerged demonstrating that in...

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PMID: 21082957
DOI: 10.1586/ehm.09.55

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