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Tumours with loss of MSH6 expression are MSI-H when screened with a pentaplex of five mononucleotide repeats

16 Nov 2010

Abstract excerpt

BACKGROUND: microsatellite instability (MSI) is commonly screened using a panel of two mononucleotide and three dinucleotide repeats as recommended by a consensus meeting on MSI tumours held at the National Cancer Institute (Bethesda, MD, USA). According to these recommendations, tumours are classified as MSI-H when at least two of the five microsatellite markers show instability, MSI-L when only one marker shows...

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PMID: 21081928
DOI: 10.1038/sj.bjc.6605988

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