Article
Patient profiling for treatment toxicity: potential use of clinical and genomic factors.
Current oncology reports - 1 Feb 2011
Armstrong Terri S, Gilbert Mark R
Abstract excerpt
Significant advances have been made in the identification of genes associated with the occurrence and prognosis of a variety of cancers. Recent efforts have also identified specific genomic single nucleotide polymorphisms (SNPs) that are associated with treatment toxicity in oncology, including toxicity associated with irinotecan, 5-FU, and 6-mercaptopurine. Despite the identification of these potential genomic...
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