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Article

Pharmacogenetics in cancer chemotherapy: balancing toxicity and response.

Therapeutic drug monitoring - 1 Apr 2004

Donnelly James G

Abstract excerpt

The goal of chemotherapy is the elimination of tumor cells from the host. This is achieved by the use of therapeutic agents that are often more harmful to normal tissues than to the targeted tumor. Many chemotherapeutic agents are designed to damage cell replication machinery either directly at the level of DNA or indirectly, by inhibiting enzymes involved with DNA repair and synthesis. Novel therapeutic agents...

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Identifiers

PMID: 15228171
DOI: 10.1097/00007691-200404000-00026

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FLT3
XRCC1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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