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Article

Distal-to-proximal NO conversion in hemoproteins: the role of the proximal pocket.

Journal of molecular biology - 14 Jan 2011

Hough Michael A, Antonyuk Svetlana V, Barbieri Sonia, Rustage Neil, McKay Alison L, Servid Amy E, Eady Robert R, Andrew Colin R, Hasnain S Samar

Abstract excerpt

Hemoproteins play central roles in the formation and utilization of nitric oxide (NO) in cellular signaling, as well as in protection against nitrosative stress. Key to heme-nitrosyl function and reactivity is the Fe coordination number (5 or 6). For (five-coordinate) 5c-NO complexes, the potential for NO to bind on either heme face exists, as in the microbial cytochrome c' from Alcaligenes xylosoxidans...

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PMID: 21073879
DOI: 10.1016/j.jmb.2010.10.035

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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