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Article

NO dioxygenase activity in hemoglobins is ubiquitous in vitro, but limited by reduction in vivo.

PloS one - 30 Apr 2008

Smagghe Benoit J, Trent James T, Hargrove Mark S

Abstract excerpt

Genomics has produced hundreds of new hemoglobin sequences with examples in nearly every living organism. Structural and biochemical characterizations of many recombinant proteins reveal reactions, like oxygen binding and NO dioxygenation, that appear general to the hemoglobin superfamily regardless of whether they are related to physiological function. Despite considerable attention to "hexacoordinate"...

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Identifiers

PMID: 18446211
DOI: 10.1371/journal.pone.0002039
PMCID: PMC2323109

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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