Article
Recent advances in molecular diagnostics of colorectal cancer by genomic arrays: proposal for a procedural shift in biological sampling and pathological report.
Italian journal of anatomy and embryology = Archivio italiano di anatomia ed embriologia - 1 Jan 2010
Castorina Sergio, Barresi Vincenza, Luca Tonia, Privitera Giovanna, Musso Nicolò, Capizzi Carmela, Condorelli Daniele Filippo
Abstract excerpt
Two forms of genetic instability have been described in colorectal cancer: chromosomal instability, characterized by structural and numerical chromosomal abnormalities and associated to aneuploidy; and microsatellite instability, characterized by a deficiency in the mismatch repair system that leads to slippage in microsatellites and is associated to euploidy. Thirteen colorectal cancer sample DNAs were analyzed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
