Article
Contribution of plasminogen activation towards the pathogenic potential of oral streptococci.
PloS one - 3 Nov 2010
Itzek Andreas, Gillen Christine M, Fulde Marcus, Friedrichs Claudia, Rodloff Arne C, Chhatwal Gursharan S, Nitsche-Schmitz Daniel Patric
Abstract excerpt
Oral streptococci are a heterogeneous group of human commensals, with a potential to cause serious infections. Activation of plasminogen has been shown to increase the virulence of typical human pathogenic streptococci such as S. pneumoniae. One important factor for plasminogen activation is the streptococcal α-enolase. Here we report that plasminogen activation is also common in oral streptococci species...
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