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Article

Genetic disorders of NaCl transport in the distal convoluted tubule.

Nephron. Physiology - 1 Jan 2011

Miller R Tyler

Abstract excerpt

The distal convoluted tubule (DCT) reabsorbs 5-10% of filtered Na, and is an important site for regulation of Na balance. Additionally, the amount and composition of the tubular fluid that leaves the DCT affects H and K secretion in more distal nephrin segments. Mutations in five genes whose prod...

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Source

Identifiers

PMID: 21071983
DOI: 10.1159/000320883

Genes

DCT
WNK1
WNK4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21071983-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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