Mutations in Na(K)Cl transporters in Gitelman's and Bartter's syndromes.

doi:10.1016/s0955-0674(98)80057-4

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Article

Mutations in Na(K)Cl transporters in Gitelman's and Bartter's syndromes.

Current opinion in cell biology - 1 Aug 1998

Simon D B, Lifton R P

Abstract excerpt

The successful merging of modern molecular genetics with basic renal physiology is exemplified by the recent description of the molecular basis of two classic diseases of clinical nephrology; Bartter's and Gitelman's syndromes of inherited hypokalemic alkalosis. Mutations in four different genes...

Topics

Bartter Syndrome
Carrier Proteins
Humans
Kidney
Mutation
Sodium-Potassium-Chloride Symporters
Syndrome

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