Article
Hedgehog signaling in cholangiocytes.
Current opinion in gastroenterology - 1 May 2011
Omenetti Alessia, Diehl Anna Mae
Abstract excerpt
PURPOSE OF REVIEW: Cells lining the biliary tree are targets of injury, but also orchestrate liver repair. The latter involves autocrine/paracrine signaling that enhances the viability and growth of residual ductular cells and promotes accumulation of inflammatory and myofibroblastic cells. The mechanisms mediating this so-called 'ductular reaction' need to be better understood to improve injury outcomes. Studies...
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