Article
Study of specific genetic and epigenetic variables in multiple myeloma.
Leukemia & lymphoma - 1 Dec 2010
Hatzimichael Eleftheria, Dasoula Aggeliki, Benetatos Leonidas, Syed Nelofer, Dranitsaris George, Crook Tim, Bourantas Konstantinos
Abstract excerpt
Few studies have examined the association between methylenetetrahydrofolate reductase (MTHFR) SNPs, epigenetic changes, and multiple myeloma (MM). We wished to determine genotype distributions for MTHFR 1298AC SNP in cases of MM and healthy controls and to examine whether there is any correlation between the methylation status of the CpG island of CDKN2A and Snk/Plk2 and MTHFR genotypes and with overall survival...
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