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Article

Polymorphisms contribution to the determination of significant risk of specific toxicities in multiple myeloma.

Klinicka onkologie : casopis Ceske a Slovenske onkologicke spolecnosti - 1 Jan 2011

Almási M, Sevcíková S, Sváhová H, Sábláková B, Májková P, Hájek R

Abstract excerpt

The introduction of new drugs improved clinical response of patients with diagnosed multiple myeloma (MM); however, MM is still an incurable disease that leads to frequent relapses. Individual genetic variability can significantly affect therapeutic response, sensitivity and toxicity. Analysis of single nucleotide polymorphisms (SNPs) to study genetic changes is the genomic method that can obtain information for...

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PMID: 21923063

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