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Article

Analysis of MTHFR polymorphisms and P16 methylation and their correlation with clinical-biological features of multiple myeloma.

Annals of hematology - 1 Jul 2006

Chiusolo Patrizia, Farina Giuliana, Putzulu Rossana, Reddiconto Giovanni, Fiorini Alessia, De Stefano Valerio, Rossi Elena, Palladino Mariangela, Leone Giuseppe, Sica Simona

Abstract excerpt

BACKGROUND: Low folate intake and changes in folate metabolism due to polymorphisms in the methylentetrahydrofolate reductase (MTHFR) gene have been associated with myelomagenesis. However, controversial data have been published regarding a protective role of variant alleles of MTHFR on MM. PATIENTS AND METHODS: To investigate the influence of two common polymorphisms of MTHFR C677T and A1298C on the risk of...

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Source

Identifiers

PMID: 16541270
DOI: 10.1007/s00277-006-0097-1

Genes

MTHFR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Analysis of MTHFR polymorphisms and P16 methylation and their correlation with clinical-biological features of multiple myeloma.PMID 16541270Read ↗

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