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Article

A CRM1-dependent nuclear export pathway is involved in the regulation of MutLα subcellular localization.

Genes, chromosomes & cancer - 1 Feb 2011

Brieger Angela, Adam Ronja, Passmann Sandra, Plotz Guido, Zeuzem Stefan, Trojan Jörg

Abstract excerpt

MutLα plays an essential role in DNA mismatch repair (MMR) and is additionally involved in other cellular mechanisms such as the regulation of cell cycle checkpoints and apoptosis. Therefore, not only germline MMR gene defects but also the subcellular localization of MutLα might be of importance...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 21064154
DOI: 10.1002/gcc.20832

Genes

MLH1
NES
PMS2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21064154-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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