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Article

MTHFR gene polymorphisms and susceptibility to rheumatoid arthritis: a meta-analysis based on 16 studies.

Clinical rheumatology - 1 Aug 2020

Bagheri-Hosseinabadi Zahra, Imani Danyal, Yousefi Hassan, Abbasifard Mitra

Abstract excerpt

Rheumatoid arthritis (RA) is the most common autoimmune rheumatic disease, in which an epigenetic implication in the disease etiopathogenesis has been noted. Here in this meta-analysis, we attempted to investigate the pooled association of methylenetetrahydrofolate reductase (MTHFR) gene C677T and A1298C polymorphisms and susceptibility to RA risk. A systematic search was performed in the main databases,...

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PMID: 32170488
DOI: 10.1007/s10067-020-05031-5

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