Article
Correlation of serum biochemical characteristics and ABCG8 genetic variant (rs 11887534) with gall stone compositions and risk of gallstone disease in Egyptian patients.
Asian journal of surgery - 1 Sept 2023
Aly Doaa Mamdouh, Fteah Asmaa Mohamed, Al Assaly Nihal M, Elashry Mohamed A, Youssef Youssef F, Hedaya Mohammed S
Abstract excerpt
BACKGROUND: The overexpression of the cholesterol transporter: ATP-binding cassette transporter (ABCG8) due to the effect of ABCG8 genetic variant (rs11887534) leads to the precipitation of cholesterol crystals and gallstone disease (GSD). OBJECTIVE: To evaluate the chemical composition of gallstones and the role of ABCG8 (rs11887534) in the susceptibility to GSD. METHODS: We enrolled 77 patients with GSD treated...
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