Article
Differential regulation of kidney and spleen cytokine responses in mice challenged with pathology-standardized doses of Candida albicans mannosylation mutants.
Infection and immunity - 1 Jan 2011
Castillo Luis, MacCallum Donna M, Brown Alistair J P, Gow Neil A R, Odds Frank C
Abstract excerpt
Cell surface polysaccharides are key determinants of host responses to fungal infection. We determined the effects of alterations in Candida albicans cell surface polysaccharide composition and gross changes in the host immune response in groups of mice challenged intravenously with five C. albicans strains at doses adjusted to give equal disease progression 3 days later. The five strains used were the parental...
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