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Article

Murine model of dextran sulfate sodium-induced colitis reveals Candida glabrata virulence and contribution of β-mannosyltransferases.

The Journal of biological chemistry - 30 Mar 2012

Jawhara Samir, Mogensen Estelle, Maggiotto François, Fradin Chantal, Sarazin Aurore, Dubuquoy Laurent, Maes Emmanuel, Guérardel Yann, Janbon Guilhem, Poulain Daniel

Abstract excerpt

Candida glabrata, like Candida albicans, is an opportunistic yeast pathogen that has adapted to colonize all segments of the human gastrointestinal tract and vagina. The C. albicans cell wall expresses β-1,2-linked mannosides (β-Mans), promoting its adherence to host cells and tissues. Because β-Mans are also present in C. glabrata, their role in C. glabrata colonization and virulence was investigated in a murine...

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Identifiers

PMID: 22291009
DOI: 10.1074/jbc.M111.329300
PMCID: PMC3322808

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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