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Article

Inhibition of recombinant N-type and native high voltage-gated neuronal Ca2+ channels by AdGABA: mechanism of action studies.

Toxicology and applied pharmacology - 1 Feb 2011

Martínez-Hernández Elizabeth, Sandoval Alejandro, González-Ramírez Ricardo, Zoidis Grigoris, Felix Ricardo

Abstract excerpt

High-voltage activated Ca(2+) (Ca(V)) channels play a key role in the regulation of numerous physiological events by causing transient changes in the intracellular Ca(2+) concentration. These channels consist of a pore-forming Ca(V)α(1) protein and three auxiliary subunits (Ca(V)β, Ca(V)α(2)δ and Ca(V)γ). Ca(V)α(2)δ is an important component of Ca(V) channels in many tissues and of great interest as a drug...

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Identifiers

PMID: 21059371
DOI: 10.1016/j.taap.2010.10.030

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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