Article
G308A polymorphism of TNF-alpha gene is associated with insulin resistance and histological changes in non alcoholic fatty liver disease patients.
Annals of hepatology - 1 Jan 2000
Aller Rocio, de Luis Daniel Antonio, Izaola Olatz, González Sagrado Manuel, Conde Rosa, Alvarez Gago Tomas, Pacheco David, González Jose Manuel, Velasco María Concepcion
Abstract excerpt
Some studies have pointed to a role of TNF-alpha in pathogenesis of non alcoholic fatty liver disease (NAFLD). The aim of our study was to investigate the influence of G308A polymorphism TNF alpha gene on the histological changes, insulin resistance and TNF-alpha levels in overweight patients. A population of 66 patients with NAFLD was recruited in a cross sectional study. A biochemical analysis of serum was...
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