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Article

Impact of Helicobacter pylori CagA diversity on gastric mucosal damage: an immunohistochemical study of East-Asian-type CagA.

Journal of gastroenterology and hepatology - 1 Apr 2011

Abe Takashi, Kodama Masaaki, Murakami Kazunari, Matsunari Osamu, Mizukami Kazuhiro, Inoue Kunimitsu, Uchida Masahiro, Okimoto Tadayoshi, Fujioka Toshio, Uchida Tomohisa, Moriyama Masatsugu, Yamaoka Yoshio

Abstract excerpt

BACKGROUND AND AIMS: Recently, we successfully produced an anti-East-Asian-type CagA-specific antibody called α-EAS Ab, which is specifically immunoreactive only with East-Asian-type CagA but not Western-type CagA. In this study, the correlations between Helicobacter pylori CagA protein diversity and gastric mucosal condition was investigated using immunohistochemical staining with α-EAS Ab in Japan. METHODS:...

Topics

Adult
Aged
Aged, 80 and over
Antigens, Bacterial
Atrophy
Bacterial Proteins
Biopsy
Female
Gastric Mucosa
Gastritis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Gastroscopy

Helicobacter Infections

Helicobacter pylori

Humans

Immunohistochemistry

Japan

Male

Metaplasia

Source

Identifiers

PMID: 21054521
DOI: 10.1111/j.1440-1746.2010.06565.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-21054521-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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