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Article

Immunohistochemical diagnosis of the cagA-gene genotype of Helicobacter pylori with anti-East Asian CagA-specific antibody.

Cancer science - 1 Apr 2007

Uchida Tomohisa, Kanada Ryoko, Tsukamoto Yoshiyuki, Hijiya Naoki, Matsuura Keiko, Yano Shinji, Yokoyama Shigeo, Kishida Tetsuko, Kodama Masaaki, Murakami Kazunari, Fujioka Toshio, Moriyama Masatsugu

Abstract excerpt

Cytotoxin-associated antigen A (CagA) protein produced by Helicobacter pylori is proposed to be associated with the pathogenesis of gastric cancer as well as gastritis and gastroduodenal ulcer. It has been reported that the CagA of H. pylori widespread in East Asian countries, where the mortality rate due to gastric cancer is high, is structurally different from that in Western countries, where the gastric cancer...

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Identifiers

PMID: 17284255
DOI: 10.1111/j.1349-7006.2007.00415.x
PMCID: PMC11158293

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