Article
Optimization of genetics to create therapies for metastatic (stage IV) non-small-cell lung cancer.
Expert opinion on pharmacotherapy - 1 Jul 2010
Rosell Rafael, Moran Teresa, Viteri Santiago, Carcereny Enric, Gasco Amaya, Quiroga Vanessa, Wei Jia, Camps Carlos, Massuti Bartomeu
Abstract excerpt
IMPORTANCE OF THE FIELD: Non-small-cell lung cancer (NSCLC) is a disseminated disease in 50% of cases, with a gloomy prognosis and median survivals of < 1 year. AREAS COVERED IN THIS REVIEW: Based on substantial advances, cancer biology insights and novel biotechnology tools, customized treatment provides hints that cisplatin-based treatment can be optimized in favorable subgroups of patients according to gene...
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