Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Inducing apoptosis in acute myeloid leukemia; mechanisms and limitations

18 Dec 2024

Abstract excerpt

Acute myeloid leukemia is the expansion of leukemic stem cells which might originate from a stem cell or a progenitor which has acquired self-renewal capacity. An aggregation of leukemic blasts in bone marrow, peripheral blood, and extramedullary tissue will result in acute myeloid leukemia. The main difficulty in treating acute myeloid leukemia is multidrug resistance, leading to treatment failure. This...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Acute Myeloid Leukemia Research
Share to Cell death mechanisms and regulation
Share to Retinoids in leukemia and cellular processes

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 39811307
DOI: 10.1016/j.heliyon.2024.e41355

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Inducing apoptosis in acute myeloid leukemia; mechanisms and limitationsPMID 39811307Read ↗

Deregulation of New Cell Death Mechanisms in LeukemiaSemantic proximity Read ↗

Targeting Apoptosis in AML: Where Do We Stand?Semantic proximity Read ↗

The Role of Apoptosis in Cancer Development and Treatment: Focusing on the Development and Treatment of Hematologic MalignanciesSemantic proximity Read ↗

Targeting Bcl-2 Proteins in Acute Myeloid LeukemiaSemantic proximity Read ↗

Receptor- and mitochondrial-mediated apoptosis in acute leukemia: a translational viewSemantic proximity Read ↗

The Role of Inhibition of Apoptosis in Acute Leukemias and Myelodysplastic SyndromeSemantic proximity Read ↗

Apoptosis as anticancer mechanism: function and dysfunction of its modulators and targeted therapeutic strategiesSemantic proximity Read ↗

Apoptosis and Pharmacological Therapies for Targeting Thereof for Cancer TherapeuticsSemantic proximity Read ↗

AML under the Scope: Current Strategies and Treatment Involving FLT3 Inhibitors and Venetoclax-Based Regimens.Semantic proximity Read ↗

Molecular Mechanisms of Apoptosis and Roles in Cancer Development and TreatmentSemantic proximity Read ↗

Targeting the mitochondrial apoptotic pathway: a preferred approach in hematologic malignancies?Semantic proximity Read ↗

Overcoming Drug Resistance by Enhancing Apoptosis of Tumor CellsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.