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Article

The pleiotropic effects of fibroblast growth factor receptors in mammalian development.

Cell structure and function - 1 Apr 2000

McIntosh I, Bellus G A, Jab E W

Abstract excerpt

In recent years the study of fibroblast growth factor receptors (FGFRs) in normal development and human genetic disorders has increased our understanding of some complex cellular processes. At least fifteen genetic disorders result from mutations within FGFR genes including skeletal dysplasias such as Apert syndrome and achondroplasia. In vitro experiments and the generation of animal models indicate that these...

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Identifiers

PMID: 10885578
DOI: 10.1247/csf.25.85

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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