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Article

Ethnic heterogeneity of IRF6 AP-2a binding site promoter SNP association with nonsyndromic cleft lip and palate.

The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association - 1 Nov 2010

Blanton Susan H, Burt Amber, Garcia Elizabeth, Mulliken John B, Stal Samuel, Hecht Jacqueline T

Abstract excerpt

OBJECTIVE: The goal of this study was to confirm the reported association between a noncoding SNP (rs642961) in IRF6 and nonsyndromic cleft lip and palate. DESIGN, SETTING, AND PARTICIPANTS: Two SNPs in IRF6 (rs2235371 and rs64296) were genotyped in Hispanic and non-Hispanic white multiplex (122) and simplex (308) nonsyndromic cleft lip and palate families. Linkage and family-based association analyses were...

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Source

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Identifiers

PMID: 21039277
DOI: 10.1597/09-153
PMCID: PMC3039881

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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