Article
Association of a fasting glucose genetic risk score with subclinical atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) study.
Diabetes - 1 Jan 2011
Rasmussen-Torvik Laura J, Li Man, Kao Wen H, Couper David, Boerwinkle Eric, Bielinski Suzette J, Folsom Aaron R, Pankow James S
Abstract excerpt
OBJECTIVE: Elevated fasting glucose level is associated with increased carotid intima-media thickness (IMT), a measure of subclinical atherosclerosis. It is unclear if this association is causal. Using the principle of Mendelian randomization, we sought to explore the causal association between circulating glucose and IMT by examining the association of a genetic risk score with IMT. RESEARCH DESIGN AND METHODS:...
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