Article
Impact of repeated measures and sample selection on genome-wide association studies of fasting glucose.
Genetic epidemiology - 1 Nov 2010
Rasmussen-Torvik Laura J, Alonso Alvaro, Li Man, Kao Wen, Köttgen Anna, Yan Yu, Couper David, Boerwinkle Eric, Bielinski Suzette J, Pankow James S
Abstract excerpt
Although genome-wide association studies (GWAS) have been performed in longitudinal studies, most used only a single trait measure. GWAS of fasting glucose have generally included only normoglycemic individuals. We examined the impact of both repeated measures and sample selection on GWAS in Atherosclerosis Risk In Communities (ARIC), a study which obtained four longitudinal measures of fasting glucose and...
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