Article
Genome-wide association and transcriptome analysis suggests total serum ghrelin to be linked with GFRAL.
European journal of endocrinology - 10 May 2021
Wittekind Dirk Alexander, Scholz Markus, Kratzsch Jürgen, Löffler Markus, Horn Katrin, Kirsten Holger, Witte Veronica, Villringer Arno, Kluge Michael
Abstract excerpt
OBJECTIVE: Ghrelin is an orexigenic peptide hormone involved in the regulation of energy homeostasis, food intake and glucose metabolism. Serum levels increase anticipating a meal and fall afterwards. Underlying genetic mechanisms of the ghrelin secretion are unknown. METHODS: Total serum ghrelin was measured in 1501 subjects selected from the population-based LIFE-ADULT-sample after an overnight fast. A...
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