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Article

Variants in the ghrelin gene are associated with metabolic syndrome in the Old Order Amish.

The Journal of clinical endocrinology and metabolism - 1 Dec 2005

Steinle Nanette I, Pollin Toni I, O'Connell Jeffrey R, Mitchell Braxton D, Shuldiner Alan R

Abstract excerpt

CONTEXT: Mature ghrelin has been shown to stimulate eating and to participate in the regulation of insulin signaling and glucose homeostasis. Its gene, GHRL, is located on chromosome 3 in a region where we have shown linkage to eating behavior, percentage body fat, and total and low-density lipoprotein cholesterol levels in subjects of the Amish Family Diabetes Study. OBJECTIVE: Our objective was to determine...

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Source

Identifiers

PMID: 16204371
DOI: 10.1210/jc.2005-0549

Genes

GHRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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