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Article

Inhibition of intestinal polyp formation by pitavastatin, a HMG-CoA reductase inhibitor.

Cancer prevention research (Philadelphia, Pa.) - 1 Mar 2011

Teraoka Naoya, Mutoh Michihiro, Takasu Shinji, Ueno Toshiya, Yamamoto Masafumi, Sugimura Takashi, Wakabayashi Keiji

Abstract excerpt

It has been suggested that hyperlipidemia is positively associated with colon carcinogenesis. Statins, 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitors, reduce serum lipid levels. In this study, we clarified the effects of a novel chemically synthesized statin, pitavastatin, on intestinal polyp formation in Min mice, and further examined serum lipid and adipocytokine levels, and proinflammatory and...

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Identifiers

PMID: 21233289
DOI: 10.1158/1940-6207.CAPR-10-0028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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