Article

Stringent proteogenomic discovery of novel small proteins in <i>Mycobacterium tuberculosis</i> clinical reference strains

2026-01-27

Abstract excerpt

Even though our meta-analysis ranks Mycobacterium tuberculosis genomes among the bacterial pathogens that are most straightforward to assemble, most available assemblies relied on short-read sequencing and contain genomic blind spots that miss functionally important genes. Complete genomes are essential for functional genomics, particularly for identifying small ORF-encoded proteins (SEPs; ≤100 amino acids), whic...

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Literature Corpus work: c36473de-cd3f-59fe-a34e-882eee44b3bc
DOI: 10.64898/2026.01.27.701740

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