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Article

Correlation of polydispersed prion protein and characteristic pathology in the thalamus in variant Creutzfeldt-Jakob disease: implication of small oligomeric species.

Brain pathology (Zurich, Switzerland) - 1 May 2011

Choi Young Pyo, Gröner Albrecht, Ironside James W, Head Mark W

Abstract excerpt

The vacuolation, neuronal loss and gliosis that characterize human prion disease pathology are accompanied by the accumulation of an aggregated, insoluble and protease-resistant form (termed PrP(Sc)) of the host-encoded normal cellular prion protein (PrP(C)). In variant Creutzfeldt-Jakob disease...

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Identifiers

PMID: 21029243
DOI: 10.1111/j.1750-3639.2010.00446.x
PMCID: PMC8094268

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-21029243-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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