Article
Differential solubility of prions is associated in manifold phenotypes.
Molecular and cellular neurosciences - 1 Nov 2009
Kuczius Thorsten, Karch Helge, Groschup Martin H
Abstract excerpt
The main feature of prion diseases is the accumulation of infectious proteins (PrP(Sc)). Since PrP(Sc) results from conversion of cellular prion proteins (PrP(C)), differential expressed PrP(C) types may play an important role in the formation and conversion efficiency to specific PrP(Sc) forms. However, little is known about the PrP(C) expression, regulation and differentiation. Here, we demonstrate a new type...
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