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Article

Helicase-inactivating mutations as a basis for dominant negative phenotypes.

Cell cycle (Georgetown, Tex.) - 15 Oct 2010

Wu Yuliang, Brosh Robert M

Abstract excerpt

There is ample evidence from studies of both unicellular and multicellular organisms that helicase-inactivating mutations lead to cellular dysfunction and disease phenotypes. In this review, we will discuss the mechanisms underlying the basis for abnormal phenotypes linked to mutations in genes e...

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Identifiers

PMID: 20980836
DOI: 10.4161/cc.9.20.13667
PMCID: PMC3055193

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20980836-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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