Article
Helicases and aging.
Cellular and molecular life sciences : CMLS - 1 May 2000
Nakura J, Ye L, Morishima A, Kohara K, Miki T
Abstract excerpt
Studying monogenic hereditary disorders that manifest age-related phenotypes in cells, tissues, and the total organism would be helpful for clarifying the mechanisms of aging. In this context, seven human disorders that manifest age-related phenotypes have been found to be caused by aberrations of five proteins with seven helicase motifs conserved in most of the helicases. These disorders are xeroderma...
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