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Article

Fanconi anemia: causes and consequences of genetic instability.

Genome dynamics - 1 Jan 2006

Kalb R, Neveling K, Nanda I, Schindler D, Hoehn H

Abstract excerpt

Fanconi anemia (FA) is a rare recessive disease that reflects the cellular and phenotypic consequences of genetic instability: growth retardation, congenital malformations, bone marrow failure, high risk of neoplasia, and premature aging. At the cellular level, manifestations of genetic instability include chromosomal breakage, cell cycle disturbance, and increased somatic mutation rates. FA cells are exquisitely...

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Source

Identifiers

PMID: 18724063
DOI: 10.1159/000092510

Genes

FANCD2
BRCA2
BRCA1
BRIP1
FANCM
RAD51

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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