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Early Events in Reovirus Infection Influence Induction of Innate Immune Response

6 Jul 2022

Abstract excerpt

Viruses must infect host cells to replicate, often killing the host cell in the process. However, hosts can activate defenses to limit viral replication and protect the organism. To trigger these host defenses to viral infections, host cells must first recognize that they are infected. Mammalian orthoreovirus (reovirus) is a model system used to study host-virus interactions. This study identifies aspects of host...

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PMID: 35867576
DOI: 10.1128/jvi.00917-22

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