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Article

The secreted integrin ligand nephronectin is necessary for forelimb formation in Xenopus tropicalis.

Developmental biology - 15 Jan 2011

Abu-Daya Anita, Nishimoto Satoko, Fairclough Lynn, Mohun Timothy J, Logan Malcolm P O, Zimmerman Lyle B

Abstract excerpt

While limb regeneration has been extensively studied in amphibians, little is known about the initial events in limb formation in metamorphosing anurans. The small secreted integrin ligand nephronectin (npnt) is necessary for development of the metanephros in mouse. Although expressed in many tissues, its role in other developmental processes is not well-studied. Here we show that a transgene insertion that...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 20977901
DOI: 10.1016/j.ydbio.2010.10.015
PMCID: PMC3021715

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