Article
Impact of polymorphisms in the renin-angiotensin-aldosterone system on hypertrophic cardiomyopathy.
Journal of the renin-angiotensin-aldosterone system : JRAAS - 1 Dec 2011
Orenes-Piñero Esteban, Hernández-Romero Diana, Jover Eva, Valdés Mariano, Lip Gregory Y H, Marín Francisco
Abstract excerpt
Hypertrophic cardiomyopathy (HCM) is a clinically heterogeneous autosomal dominant heart disease characterised by left ventricular hypertrophy in the absence of another cardiac or systemic disease that is capable of producing significant wall thickening. Microscopically it is characterised by cardiomyocyte hypertrophy, myofibrillar disarray and fibrosis. The phenotypic expression of HCM is multifactorial, with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
