Impact of angiotensin I converting enzyme insertion/deletion polymorphisms on dilated cardiomyopathy and hypertrophic cardiomyopathy risk.

doi:10.1371/journal.pone.0063309

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Article

Impact of angiotensin I converting enzyme insertion/deletion polymorphisms on dilated cardiomyopathy and hypertrophic cardiomyopathy risk.

PloS one - 1 Jan 2013

Yang Jianmin, Zhao Yunhan, Hao Panpan, Meng Xiao, Dong Mei, Wang Ying, Zhang Yun, Zhang Cheng

Abstract excerpt

BACKGROUND: Genetic factors in the pathogenesis of cardiomyopathies have received a lot attention during the past two decades. Angiotensin I converting enzyme (ACE) insertion/deletion (I/D) polymorphisms were found to be associated with cardiomyopathies. However, the previous results were inconsistent. The current meta-analysis aims to examine the association of ACE I/D polymorphisms and dilated cardiomyopathy...

Topics

Cardiomyopathy, Dilated
Cardiomyopathy, Hypertrophic
Genetic Predisposition to Disease
Humans
INDEL Mutation
Peptidyl-Dipeptidase A
Polymorphism, Genetic

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PMID: 23691019
DOI: 10.1371/journal.pone.0063309
PMCID: PMC3653933

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