Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Impact of systolic dysfunction in genotyped hypertrophic cardiomyopathy.

Clinical cardiology - 1 Mar 2013

Fujino Noboru, Konno Tetsuo, Hayashi Kenshi, Hodatsu Akihiko, Fujita Takashi, Tsuda Toyonobu, Nagata Yoji, Kawashiri Masa-aki, Ino Hidekazu, Yamagishi Masakazu

Abstract excerpt

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is a disease of the sarcomere, and approximately 5% of cases of HCM show systolic dysfunction with poor prognosis. Few data exist regarding the systolic dysfunction in a large population of genotyped HCM subjects. HYPOTHESIS: The aim of this study was to assess the systolic dysfunction and prognosis in sarcomere gene mutation carriers. METHODS: The study included 157...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cardiomyopathy, Hypertrophic
Share to Kaplan-Meier Estimate

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Proportional Hazards Models

Share to Stroke Volume

Share to Systole

Share to Ultrasonography

Share to Ventricular Dysfunction, Left

Share to Ventricular Function, Left

Source

Open in PubMed Open full text

Identifiers

PMID: 23197398
DOI: 10.1002/clc.22082
PMCID: PMC6649536

Genes

MYBPC3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Impact of systolic dysfunction in genotyped hypertrophic cardiomyopathy.PMID 23197398Read ↗

Long-Term Prevalence of Systolic Dysfunction in MYBPC3 Versus MYH7-Related Hypertrophic Cardiomyopathy.Semantic proximity Read ↗

Clinical outcomes associated with sarcomere mutations in hypertrophic cardiomyopathy: a meta-analysis on 7675 individuals.Semantic proximity Read ↗

Disease penetrance and risk stratification for sudden cardiac death in asymptomatic hypertrophic cardiomyopathy mutation carriers.Semantic proximity Read ↗

Genotype-phenotype associations in sarcomeric hypertrophic cardiomyopathy associated with mutations in the MYBPC3 gene: Systematic review and meta-analysis.Semantic proximity Read ↗

Hypertrophic cardiomyopathy in MYBPC3 carriers in agingSemantic proximity Read ↗

Genetic determinants of clinical phenotype in hypertrophic cardiomyopathy.Semantic proximity Read ↗

Double or compound sarcomere mutations in hypertrophic cardiomyopathy: a potential link to sudden death in the absence of conventional risk factors.Semantic proximity Read ↗

Gender- and age-related differences in distinct phenotypes of hypertrophic cardiomyopathy-associated mutation MYBPC3-E334K.Semantic proximity Read ↗

Lifelong Clinical Impact of the Presence of Sarcomere Gene Mutation in Japanese Patients With Hypertrophic Cardiomyopathy.Semantic proximity Read ↗

Homozygous missense MYBPC3 Pro873His mutation associated with increased risk for heart failure development in hypertrophic cardiomyopathy.Semantic proximity Read ↗

The yield of risk stratification for sudden cardiac death in hypertrophic cardiomyopathy myosin-binding protein C gene mutation carriers: focus on predictive screening.Semantic proximity Read ↗

Sex-Specific Clinical and Genetic Factors Associated with Adverse Outcomes in Hypertrophic CardiomyopathySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.