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Article

Mutations in mitochondrial complex III uniquely affect complex I in Caenorhabditis elegans.

The Journal of biological chemistry - 24 Dec 2010

Suthammarak Wichit, Morgan Phil G, Sedensky Margaret M

Abstract excerpt

Mitochondrial supercomplexes containing complexes I, III, and IV of the electron transport chain are now regarded as an established entity. Supercomplex I·III·IV has been theorized to improve respiratory chain function by allowing quinone channeling between complexes I and III. Here, we show that the role of the supercomplexes extends beyond channeling. Mutant analysis in Caenorhabditis elegans reveals that...

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Identifiers

PMID: 20971856
DOI: 10.1074/jbc.M110.159608
PMCID: PMC3003372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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