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Article

[Azathioprine-associated severe myelosuppression: indication of routine determination of thiopurine S-methyltransferase variant?].

La Revue de medecine interne - 1 Jun 2011

Ngo S, Sauvetre G, Vittecoq O, Lévesque H, Marie I

Abstract excerpt

INTRODUCTION: Myelotoxicity is a well-known adverse effect of azathioprine, leading mainly to leukopenia. Other azathioprine associated hematological adverse effects are uncommon. CASE REPORT: We report a 49-year-old woman with rheumatoid arthritis and acquired hemophilia, who presented a severe myelosuppression occurring 3 weeks after an increase of her azathioprine regimen (at a daily dose of 150 mg). The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20970225
DOI: 10.1016/j.revmed.2010.09.006

Genes

TPMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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