Article
Thiopurine S-methyltransferase genotypic analysis in autoimmune bullous diseases.
European journal of dermatology : EJD - 1 Jan 2000
Bezier Maud, Reguiai Ziad, Vitry Fabien, Broly Franck, Bernard Philippe
Abstract excerpt
Thiopurine S-methyltransferase (TPMT) activity is inversely related to the risk of developing severe hematopoietic toxicity in patients treated with azathioprine. The aim of this study was to evaluate the usefulness of TPMT genotyping in severe cases of autoimmune bullous diseases treated with azathioprine. A retrospective study of TPMT genotyping was performed in patients with autoimmune bullous diseases...
Topics
- Adult
- Aged
- Aged, 80 and over
- Autoimmune Diseases
- Female
- Genotype
- Humans
- Male
- Methyltransferases
- Middle Aged
- Retrospective Studies
- Skin Diseases, Vesiculobullous
