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Article

Myasthenia gravis and azathioprine treatment: Adverse events related to thiopurine S-methyl-transferase (TPMT) polymorphisms.

Journal of the neurological sciences - 15 May 2020

Lorenzoni Paulo José, Kay Cláudia Suemi Kamoi, Zanlorenzi Marcelo Farago, Ducci Renata Dal-Prá, Werneck Lineu Cesar, Scola Rosana Herminia

Abstract excerpt

Azathioprine (AZA) is the most common immunosuppressive drug used to treat myasthenia gravis (MG). To analyses the prevalence of thiopurine S-methyl-transferase (TPMT) genotypes and their association with adverse events due to azathioprine therapy in MG patients. Allele-specific polymerase chain reaction (PCR) and PCR with restriction fragment length polymorphism (RFLP) analysis were carried out to determine the...

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PMID: 32070863
DOI: 10.1016/j.jns.2020.116734

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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