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Article

Leu628 of the KIX domain of CBP is a key residue for the interaction with the MLL transactivation domain.

FEBS letters - 19 Nov 2010

Arai Munehito, Dyson H Jane, Wright Peter E

Abstract excerpt

Physical interaction between the transactivation domain (TAD) of the mixed-lineage leukemia protein (MLL) and the KIX domain of the cyclic-AMP response element binding protein (CREB) binding protein (CBP) is necessary for MLL-mediated transcriptional activation. We show by alanine-scanning mutage...

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Identifiers

PMID: 20969867
DOI: 10.1016/j.febslet.2010.10.024
PMCID: PMC2993637

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20969867-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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