Article
Ataxia telangiectasia.
Seminars in pediatric neurology - 1 Dec 1998
Crawford T O
Abstract excerpt
The cloning of ATM in 1995, the gene responsible for ataxia-telangiectasia, opened a dimension of biological research that is as complex and intriguing to cell biologists as this classic disorder has been to clinicians for four decades. The phenotype is both variable and stereotyped, with signifi...
Topics
- Adolescent
- Animals
- Ataxia Telangiectasia
- Child
- DNA Mutational Analysis
- Diagnosis, Differential
- Genetic Counseling
- Genetic Predisposition to Disease
- Humans
- Mice
- Mice, Transgenic
- Models, Genetic
- Phosphatidylinositol 3-Kinases