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Article

The versatile functions of ATM kinase

1 Jan 2014

Abstract excerpt

G enetic diseases with cancer predisposition phenotypes provide insights into essential roles of the involved genes and their products in the maintenance of genome stability, as genome instability is one of the hallmarks of cancer. Ataxia-telangiectasia (A-T), a rare autosomal recessive disorder, is such an example. A-T is caused by mutations in the ataxia-telangiectasia mutated (ATM) gene, located on human...

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PMID: 24667671
DOI: 10.4103/2319-4170.125655

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